Synergistic cellular effects including mitochondrial destabilization, autophagy and apoptosis following low-level exposure to a mixture of lipophilic persistent organic pollutants
Abstract Humans are exposed to multiple exogenous environmental pollutants.Many of these compounds are parts of mixtures that can exacerbate harmful effects of the individual mixture components.2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is primarily produced via industrial processes including incineration and the manufacture of herbicides.Both end